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Altered (transition) states: Mechanisms of solution and enzyme catalyzed RNA 2′-O-transphosphorylation
Although there have been great strides in defining the mechanisms of RNA strand cleavage by 2′-O-transphosphorylation, long-standing questions remain. How do different catalytic modes such as acid/base and metal ion catalysis influence transition state charge distribution? Does the large rate enhanc...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149925/ https://ncbi.nlm.nih.gov/pubmed/25023967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.06.010 |
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