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Dissecting allosteric effects of activator–coactivator complexes using a covalent small molecule ligand

Allosteric binding events play a critical role in the formation and stability of transcriptional activator–coactivator complexes, perhaps in part due to the often intrinsically disordered nature of one or more of the constituent partners. The kinase-inducible domain interacting (KIX) domain of the m...

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書目詳細資料
Main Authors: Wang, Ningkun, Lodge, Jean M., Fierke, Carol A., Mapp, Anna K.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143068/
https://ncbi.nlm.nih.gov/pubmed/25049401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406033111
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