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Dissecting allosteric effects of activator–coactivator complexes using a covalent small molecule ligand

Allosteric binding events play a critical role in the formation and stability of transcriptional activator–coactivator complexes, perhaps in part due to the often intrinsically disordered nature of one or more of the constituent partners. The kinase-inducible domain interacting (KIX) domain of the m...

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Detalhes bibliográficos
Main Authors: Wang, Ningkun, Lodge, Jean M., Fierke, Carol A., Mapp, Anna K.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143068/
https://ncbi.nlm.nih.gov/pubmed/25049401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1406033111
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