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Poly (ADP-ribose) polymerase inhibitor CEP-8983 synergizes with bendamustine in chronic lymphocytic leukemia cells in vitro
DNA repair aberrations and associated chromosomal instability is a feature of chronic lymphocytic leukemia (CLL). To evaluate if DNA repair insufficiencies are related to methylation changes, we examined the methylation of nine promoter regions of DNA repair proteins by bisulfide sequencing in 26 CL...
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主要な著者: | , , , , , , , |
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フォーマット: | Artigo |
言語: | Inglês |
出版事項: |
2013
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主題: | |
オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142574/ https://ncbi.nlm.nih.gov/pubmed/24439051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.12.019 |
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