Involvement of homologous recombination in the synergism between cisplatin and poly (ADP‐ribose) polymerase inhibition

Poly (ADP‐ribose) polymerase (PARP) plays a critical role in responding to DNA damage, by activating DNA repair pathways responsible for cellular survival. Inhibition of PARP is used to treat certain solid cancers, such as breast and ovarian cancers. However, its effectiveness with other solid cance...

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Publicat a:Cancer Sci
Autors principals: Sakogawa, Kenji, Aoki, Yoshiro, Misumi, Keizo, Hamai, Yoichi, Emi, Manabu, Hihara, Jun, Shi, Lin, Kono, Kazuteru, Horikoshi, Yasunori, Sun, Jiying, Ikura, Tsuyoshi, Okada, Morihito, Tashiro, Satoshi
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2013
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653531/
https://ncbi.nlm.nih.gov/pubmed/24033642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12281
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