Involvement of homologous recombination in the synergism between cisplatin and poly (ADP‐ribose) polymerase inhibition

Poly (ADP‐ribose) polymerase (PARP) plays a critical role in responding to DNA damage, by activating DNA repair pathways responsible for cellular survival. Inhibition of PARP is used to treat certain solid cancers, such as breast and ovarian cancers. However, its effectiveness with other solid cance...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Sakogawa, Kenji, Aoki, Yoshiro, Misumi, Keizo, Hamai, Yoichi, Emi, Manabu, Hihara, Jun, Shi, Lin, Kono, Kazuteru, Horikoshi, Yasunori, Sun, Jiying, Ikura, Tsuyoshi, Okada, Morihito, Tashiro, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2013
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653531/
https://ncbi.nlm.nih.gov/pubmed/24033642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12281
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