Involvement of homologous recombination in the synergism between cisplatin and poly (ADP‐ribose) polymerase inhibition

Poly (ADP‐ribose) polymerase (PARP) plays a critical role in responding to DNA damage, by activating DNA repair pathways responsible for cellular survival. Inhibition of PARP is used to treat certain solid cancers, such as breast and ovarian cancers. However, its effectiveness with other solid cance...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Cancer Sci
Main Authors: Sakogawa, Kenji, Aoki, Yoshiro, Misumi, Keizo, Hamai, Yoichi, Emi, Manabu, Hihara, Jun, Shi, Lin, Kono, Kazuteru, Horikoshi, Yasunori, Sun, Jiying, Ikura, Tsuyoshi, Okada, Morihito, Tashiro, Satoshi
פורמט: Artigo
שפה:Inglês
יצא לאור: John Wiley and Sons Inc. 2013
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653531/
https://ncbi.nlm.nih.gov/pubmed/24033642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12281
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