Involvement of homologous recombination in the synergism between cisplatin and poly (ADP‐ribose) polymerase inhibition

Poly (ADP‐ribose) polymerase (PARP) plays a critical role in responding to DNA damage, by activating DNA repair pathways responsible for cellular survival. Inhibition of PARP is used to treat certain solid cancers, such as breast and ovarian cancers. However, its effectiveness with other solid cance...

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Detaylı Bibliyografya
Yayımlandı:Cancer Sci
Asıl Yazarlar: Sakogawa, Kenji, Aoki, Yoshiro, Misumi, Keizo, Hamai, Yoichi, Emi, Manabu, Hihara, Jun, Shi, Lin, Kono, Kazuteru, Horikoshi, Yasunori, Sun, Jiying, Ikura, Tsuyoshi, Okada, Morihito, Tashiro, Satoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: John Wiley and Sons Inc. 2013
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7653531/
https://ncbi.nlm.nih.gov/pubmed/24033642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12281
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