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Enhanced gefitinib‐induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia‐mutated kinase inhibition in non‐small‐cell lung cancer cells

The epidermal growth factor receptor (EGFR) tyrosine kinase signaling pathways regulate cellular activities. The EGFR tyrosine kinase inhibitors (EGFR‐TKIs) repress the EGFR pathway constitutively activated by somatic EGFR gene mutations and have drastically improved the prognosis of non‐small‐cell...

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Détails bibliographiques
Publié dans:Cancer Sci
Auteurs principaux: Misumi, Keizo, Sun, Jiying, Kinomura, Aiko, Miyata, Yoshihiro, Okada, Morihito, Tashiro, Satoshi
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832868/
https://ncbi.nlm.nih.gov/pubmed/26825989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12899
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