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Enhanced gefitinib‐induced repression of the epidermal growth factor receptor pathway by ataxia telangiectasia‐mutated kinase inhibition in non‐small‐cell lung cancer cells

The epidermal growth factor receptor (EGFR) tyrosine kinase signaling pathways regulate cellular activities. The EGFR tyrosine kinase inhibitors (EGFR‐TKIs) repress the EGFR pathway constitutively activated by somatic EGFR gene mutations and have drastically improved the prognosis of non‐small‐cell...

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Detalhes bibliográficos
Publicado no:Cancer Sci
Main Authors: Misumi, Keizo, Sun, Jiying, Kinomura, Aiko, Miyata, Yoshihiro, Okada, Morihito, Tashiro, Satoshi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4832868/
https://ncbi.nlm.nih.gov/pubmed/26825989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12899
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