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Novel modulators of poly(ADP-ribose) polymerase

The nuclear enzyme poly(ADP-ribose) polymerase (PARP)-1 has an important role in regulating cell death and cellular responses to DNA repair. Pharmacological inhibitors of PARP have entered clinical testing as cytoprotective agents in cardiovascular diseases and as adjunct antitumor therapeutics. Ini...

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Bibliografiske detaljer
Main Authors: Szabo, Csaba, Pacher, Pal, Swanson, Raymond A.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2228253/
https://ncbi.nlm.nih.gov/pubmed/17055069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tips.2006.10.003
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