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Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure

Overactivation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) contributes to the development of cell dysfunction and tissue injury in various pathophysiological conditions associated with oxidative and nitrosative stress, including myocardial reperfusion injury, heart transplantation, diab...

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Main Authors: PACHER, PÁL, LIAUDET, LUCAS, MABLEY, JON G., CZIRÁKI, ATTILA, HASKÓ, GYÖRGY, SZABÓ, CSABA
Formato: Artigo
Idioma:Inglês
Publicado: 2006
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2245862/
https://ncbi.nlm.nih.gov/pubmed/16391839
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