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Poly(ADP-ribose) polymerase is a regulator of chemokine production: relevance for the pathogenesis of shock and inflammation.

BACKGROUND: Chemokines are key regulators of leukocyte traffic in various forms of inflammation and reperfusion injury. There is emerging evidence that the activation of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) importantly contributes to the up-regulation of a variety of proinflammatory...

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Bibliografske podrobnosti
Main Authors: Haskó, György, Mabley, Jon G., Németh, Zoltán H., Pacher, Pál, Deitch, Edwin A., Szabó, Csaba
Format: Artigo
Jezik:Inglês
Izdano: 2002
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2039990/
https://ncbi.nlm.nih.gov/pubmed/12359959
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