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Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation
Recent work has demonstrated the production of reactive oxygen and nitrogen species in the vasculature of aging animals. Oxidant induced cell injury triggers the activation of nuclear enzyme poly(ADP ribose) polymerase (PARP) leading to endothelial dysfunction in various pathophysiological condition...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2002
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573277/ https://ncbi.nlm.nih.gov/pubmed/11906946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704627 |
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