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Endothelial dysfunction in aging animals: the role of poly(ADP-ribose) polymerase activation
Recent work has demonstrated the production of reactive oxygen and nitrogen species in the vasculature of aging animals. Oxidant induced cell injury triggers the activation of nuclear enzyme poly(ADP ribose) polymerase (PARP) leading to endothelial dysfunction in various pathophysiological condition...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1573277/ https://ncbi.nlm.nih.gov/pubmed/11906946 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704627 |
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