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Mechanism of gate opening in the 20S proteasome by the proteasomal ATPases
Substrates enter the cylindrical 20S proteasome through a gated channel that is regulated by the ATPases in the 19S regulatory particle in eukaryotes or the homologous PAN ATPase complex in archaea. These ATPases contain a conserved C-terminal hydrophobic-tyrosine-X (HbYX) motif that triggers gate o...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4141531/ https://ncbi.nlm.nih.gov/pubmed/18471981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.03.004 |
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