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Allosteric coupling between α-rings of the 20S proteasome

Proteasomal machinery performs essential regulated protein degradation in eukaryotes. Classic proteasomes are symmetric, with a regulatory ATPase docked at each end of the cylindrical 20S. Asymmetric complexes are also present in cells, either with a single ATPase or with an ATPase and non-ATPase at...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Yu, Zanlin, Yu, Yadong, Wang, Feng, Myasnikov, Alexander G., Coffino, Philip, Cheng, Yifan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7486400/
https://ncbi.nlm.nih.gov/pubmed/32917864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18415-7
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