تحميل...

Structural basis for highly effective HIV-1 neutralization by CD4-mimetic miniproteins revealed by 1.5 Å co-crystal structure of gp120 and M48U1

The interface between HIV-1 gp120 envelope glycoprotein and CD4 receptor contains an unusual interfacial cavity, the “Phe43 cavity”, which miniprotein mimetics of CD4 with non-natural extensions can potentially utilize to enhance their neutralization of HIV-1. Here we report co-crystal structures of...

وصف كامل

محفوظ في:

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون:	Acharya, Priyamvada, Luongo, Timothy, Louder, Mark K., McKee, Krisha, Yang, Yongping, Kwon, Young Do, Mascola, John R., Kessler, Pascal, Martin, Loïc, Kwong, Peter D.
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	2013
الموضوعات:	Article
الوصول للمادة أونلاين:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4140785/ https://ncbi.nlm.nih.gov/pubmed/23707685 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2013.04.015
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!

Structural basis for highly effective HIV-1 neutralization by CD4-mimetic miniproteins revealed by 1.5 Å co-crystal structure of gp120 and M48U1

مواد مشابهة