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HIV-1 gp120 as a therapeutic target: Navigating a moving labyrinth
INTRODUCTION: The HIV-1 gp120 envelope (Env) glycoprotein mediates attachment of virus to human target cells that display requisite receptors, CD4 and co-receptor, generally CCR5. Despite high affinity interactions with host receptors and proof-of-principle by the drug maraviroc that interference wi...
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| Publié dans: | Expert Opin Ther Targets |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4711772/ https://ncbi.nlm.nih.gov/pubmed/25724219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2015.1010513 |
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