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Supersaturation-limited Amyloid Fibrillation of Insulin Revealed by Ultrasonication
Amyloid fibrils form in supersaturated solutions via a nucleation and growth mechanism. We proposed that ultrasonication may be an effective agitation to trigger nucleation that would otherwise not occur under the persistent metastability of supersaturation. However, the roles of supersaturation and...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140283/ https://ncbi.nlm.nih.gov/pubmed/24847058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.566950 |
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