Universal Artificial Antigen Presenting Cells to Selectively Propagate T Cells Expressing Chimeric Antigen Receptor Independent of Specificity

T cells genetically modified to stably express immunoreceptors are being assessed for therapeutic potential in clinical trials. T cells expressing a chimeric antigen receptor (CAR) are endowed with a new specificity to target tumor-associated antigen (TAA) independent of major histocompatibility com...

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Detalhes bibliográficos
Main Authors: Rushworth, David, Jena, Bipulendu, Olivares, Simon, Maiti, Sourindra, Briggs, Neima, Somanchi, Srinivas, Dai, Jianliang, Lee, Dean, Cooper, Laurence J. N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139067/
https://ncbi.nlm.nih.gov/pubmed/24714354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000032
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