Caricamento...
Redirecting T-cell specificity to EGFR using mRNA to self-limit expression of chimeric antigen receptor
Potential for on-target, but off-tissue toxicity limits therapeutic application of genetically modified T cells constitutively expressing chimeric antigen receptors (CARs) from tumor-associated antigens expressed normal tissue, such as epidermal growth factor receptor (EGFR). Curtailing expression o...
Salvato in:
| Pubblicato in: | J Immunother |
|---|---|
| Autori principali: | , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5847343/ https://ncbi.nlm.nih.gov/pubmed/27163741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000126 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|