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Translational Implications for Off-the-shelf Immune Cells Expressing Chimeric Antigen Receptors
Chimeric antigen receptor (CAR) endows specificity to T-cells independent of human leukocyte antigen (HLA). This enables one immunoreceptor to directly target the same surface antigen on different subsets of tumor cells from multiple HLA-disparate recipients. Most approaches manufacture individualiz...
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| Publicado en: | Mol Ther |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5088751/ https://ncbi.nlm.nih.gov/pubmed/27203439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2016.106 |
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