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The human application of gene therapy to re-program T-cell specificity using chimeric antigen receptors

The adoptive transfer of T cells is a promising approach to treat cancers. Primary human T cells can be modified using viral and non-viral vectors to promote the specific targeting of cancer cells via the introduction of exogenous T-cell receptors (TCRs) or chimeric antigen receptors (CARs). This ge...

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Detalhes bibliográficos
Main Authors: Guerrero, Alan D, Moyes, Judy S, Cooper, Laurence JN
Formato: Artigo
Idioma:Inglês
Publicado em: Sun Yat-sen University Cancer Center 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4190432/
https://ncbi.nlm.nih.gov/pubmed/25189715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5732/cjc.014.10100
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