Carregant...
Copper is required for oncogenic BRAF signaling and tumorigenesis
The BRAF kinase is mutated, typically V600E, to induce an active oncogenic state in a large fraction of melanoma, thyroid, hairy cell leukemia, and to a lesser extent, a wide spectrum of other cancers(1,2). BRAF(V600E) phosphorylates and activates the kinases MEK1 and MEK2, which in turn phosphoryla...
Guardat en:
| Autors principals: | , , , , , , , , , , |
|---|---|
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4138975/ https://ncbi.nlm.nih.gov/pubmed/24717435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13180 |
| Etiquetes: |
Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|