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Successful challenges using native E. coli asparaginase after hypersensitivity reactions to PEGylated E. coli asparaginase
PURPOSE: Asparaginase is an essential component of pediatric acute lymphoblastic leukemia (ALL) therapy. However, asparaginase-induced hypersensitivity reactions can compromise its efficacy either by directly influencing the pharmacokinetics of asparaginase or by leading to a discontinuation of aspa...
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| Main Authors: | , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4137479/ https://ncbi.nlm.nih.gov/pubmed/24771103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2464-2 |
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