A Specific Polymorphism in Mycobacterium tuberculosis H37Rv Causes Differential ESAT-6 Expression and Identifies WhiB6 as a Novel ESX-1 Component

The ESX-1 secreted virulence factor ESAT-6 is one of the major and most well-studied virulence factors of Mycobacterium tuberculosis, given that its inactivation severely attenuates virulent mycobacteria. In this work, we show that clinical isolates of M. tuberculosis produce and secrete larger amou...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Solans, Luis, Aguiló, Nacho, Samper, Sofía, Pawlik, Alexandre, Frigui, Wafa, Martín, Carlos, Brosch, Roland, Gonzalo-Asensio, Jesús
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Molecular Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136221/
https://ncbi.nlm.nih.gov/pubmed/24891105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01824-14
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados