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Integrated transcriptomic and proteomic analysis of pathogenic mycobacteria and their esx-1 mutants reveal secretion-dependent regulation of ESX-1 substrates and WhiB6 as a transcriptional regulator

The mycobacterial type VII secretion system ESX-1 is responsible for the secretion of a number of proteins that play important roles during host infection. The regulation of the expression of secreted proteins is often essential to establish successful infection. Using transcriptome sequencing, we f...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:PLoS One
मुख्य लेखकों: Abdallah, Abdallah M., Weerdenburg, Eveline M., Guan, Qingtian, Ummels, Roy, Borggreve, Stephanie, Adroub, Sabir A., Malas, Tareq B., Naeem, Raeece, Zhang, Huoming, Otto, Thomas D., Bitter, Wilbert, Pain, Arnab
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6343904/
https://ncbi.nlm.nih.gov/pubmed/30673778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0211003
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