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WhiB6 regulation of ESX-1 gene expression is controlled by a negative feedback loop in Mycobacterium marinum

ESX (ESAT-6 system) export systems play diverse roles across mycobacterial species. Interestingly, genetic disruption of ESX systems in different species does not result in an accumulation of protein substrates in the mycobacterial cell. However, the mechanisms underlying this observation are elusiv...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bosserman, Rachel E., Nguyen, Tiffany T., Sanchez, Kevin G., Chirakos, Alexandra E., Ferrell, Micah J., Thompson, Cristal R., Champion, Matthew M., Abramovitch, Robert B., Champion, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740670/
https://ncbi.nlm.nih.gov/pubmed/29180415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710167114
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