WhiB6 regulation of ESX-1 gene expression is controlled by a negative feedback loop in Mycobacterium marinum

ESX (ESAT-6 system) export systems play diverse roles across mycobacterial species. Interestingly, genetic disruption of ESX systems in different species does not result in an accumulation of protein substrates in the mycobacterial cell. However, the mechanisms underlying this observation are elusiv...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Bosserman, Rachel E., Nguyen, Tiffany T., Sanchez, Kevin G., Chirakos, Alexandra E., Ferrell, Micah J., Thompson, Cristal R., Champion, Matthew M., Abramovitch, Robert B., Champion, Patricia A.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2017
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5740670/
https://ncbi.nlm.nih.gov/pubmed/29180415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710167114
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