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Esx Paralogs Are Functionally Equivalent to ESX-1 Proteins but Are Dispensable for Virulence in Mycobacterium marinum

Mycobacterium marinum is a nontuberculous pathogen of poikilothermic fish and an opportunistic human pathogen. Like tuberculous mycobacteria, the M. marinum M strain requires the ESX-1 (ESAT-6 system 1) secretion system for virulence in host cells. EsxB and EsxA, two major virulence factors exported...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Bosserman, Rachel E., Thompson, Cristal Reyna, Nicholson, Kathleen R., Champion, Patricia A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952400/
https://ncbi.nlm.nih.gov/pubmed/29555701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00726-17
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