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Dissecting Mechanisms of Immunodominance to the Common TB Antigens ESAT-6, CFP10, Rv2031c (hspX), Rv2654c (TB7.7) and Rv1038c (EsxJ)

Diagnosis of tuberculosis often relies on the ex vivo interferon gamma release assays QuantiFERON-TB Gold In-Tube and T-SPOT.TB. However, understanding of the immunological mechanisms underlying their diagnostic utility is still incomplete. Accordingly, we investigated T cell responses for the TB an...

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Detalhes bibliográficos
Main Authors: Arlehamn, Cecilia S. Lindestam, Sidney, John, Henderson, Ryan, Greenbaum, Jason A., James, Eddie A., Moutaftsi, Magdalini, Coler, Rhea, McKinney, Denise M., Park, Daniel, Taplitz, Randy, Kwok, William W., Grey, Howard, Peters, Bjoern, Sette, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345088/
https://ncbi.nlm.nih.gov/pubmed/22504645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103556
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