A Specific Polymorphism in Mycobacterium tuberculosis H37Rv Causes Differential ESAT-6 Expression and Identifies WhiB6 as a Novel ESX-1 Component

Por Solans, Luis, Aguiló, Nacho, Samper, Sofía, Pawlik, Alexandre, Frigui, Wafa, Martín, Carlos, Brosch, Roland, Gonzalo-Asensio, Jesús
Publicado em 2014

Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes

Por Dubois, Violaine, Laencina, Laura, Bories, Anouchka, Le Moigne, Vincent, Pawlik, Alexandre, Herrmann, Jean-Louis, Girard-Misguich, Fabienne
Publicado no J Vis Exp (2018)

Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis

Por Le Chevalier, Fabien, Cascioferro, Alessandro, Frigui, Wafa, Pawlik, Alexandre, Boritsch, Eva C., Bottai, Daria, Majlessi, Laleh, Herrmann, Jean Louis, Brosch, Roland
Publicado no Sci Rep (2015)

Evolutionary history of tuberculosis shaped by conserved mutations in the PhoPR virulence regulator

Por Gonzalo-Asensio, Jesús, Malaga, Wladimir, Pawlik, Alexandre, Astarie-Dequeker, Catherine, Passemar, Charlotte, Moreau, Flavie, Laval, Françoise, Daffé, Mamadou, Martin, Carlos, Brosch, Roland, Guilhot, Christophe
Publicado em 2014

Key experimental evidence of chromosomal DNA transfer among selected tuberculosis-causing mycobacteria

Por Boritsch, Eva C., Khanna, Varun, Pawlik, Alexandre, Honoré, Nadine, Navas, Victor H., Ma, Laurence, Bouchier, Christiane, Seemann, Torsten, Supply, Philip, Stinear, Timothy P., Brosch, Roland
Publicado no Proc Natl Acad Sci U S A (2016)

Lsr2 Is an Important Determinant of Intracellular Growth and Virulence in Mycobacterium abscessus

Por Le Moigne, Vincent, Bernut, Audrey, Cortès, Mélanie, Viljoen, Albertus, Dupont, Christian, Pawlik, Alexandre, Gaillard, Jean-Louis, Misguich, Fabienne, Crémazy, Frédéric, Kremer, Laurent, Herrmann, Jean-Louis
Publicado no Front Microbiol (2019)

CD4(+) T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection

Por Sayes, Fadel, Pawlik, Alexandre, Frigui, Wafa, Gröschel, Matthias I., Crommelynck, Samuel, Fayolle, Catherine, Cia, Felipe, Bancroft, Gregory J., Bottai, Daria, Leclerc, Claude, Brosch, Roland, Majlessi, Laleh
Publicado no PLoS Pathog (2016)

Unexpected Genomic and Phenotypic Diversity of Mycobacterium africanum Lineage 5 Affects Drug Resistance, Protein Secretion, and Immunogenicity

Por Ates, Louis S, Dippenaar, Anzaan, Sayes, Fadel, Pawlik, Alexandre, Bouchier, Christiane, Ma, Laurence, Warren, Robin M, Sougakoff, Wladimir, Majlessi, Laleh, van Heijst, Jeroen W J, Brossier, Florence, Brosch, Roland
Publicado no Genome Biol Evol (2018)

Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

Por Dubois, Violaine, Pawlik, Alexandre, Bories, Anouchka, Le Moigne, Vincent, Sismeiro, Odile, Legendre, Rachel, Varet, Hugo, Rodríguez-Ordóñez, María del Pilar, Gaillard, Jean-Louis, Coppée, Jean-Yves, Brosch, Roland, Herrmann, Jean-Louis, Girard-Misguich, Fabienne
Publicado no PLoS Pathog (2019)

TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages

Por Bottai, Daria, Frigui, Wafa, Sayes, Fadel, Di Luca, Mariagrazia, Spadoni, Dalila, Pawlik, Alexandre, Zoppo, Marina, Orgeur, Mickael, Khanna, Varun, Hardy, David, Mangenot, Sophie, Barbe, Valerie, Medigue, Claudine, Ma, Laurence, Bouchier, Christiane, Tavanti, Arianna, Larrouy-Maumus, Gerald, Brosch, Roland
Publicado no Nat Commun (2020)

Genome analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of the etiologic agent of tuberculosis

Por Supply, Philip, Marceau, Michael, Mangenot, Sophie, Roche, David, Rouanet, Carine, Khanna, Varun, Majlessi, Laleh, Criscuolo, Alexis, Tap, Julien, Pawlik, Alexandre, Fiette, Laurence, Orgeur, Mickael, Fabre, Michel, Parmentier, Cécile, Frigui, Wafa, Simeone, Roxane, Boritsch, Eva C., Debrie, Anne-Sophie, Willery, Eve, Walker, Danielle, Quail, Michael A., Ma, Laurence, Bouchier, Christiane, Salvignol, Grégory, Sayes, Fadel, Cascioferro, Alessandro, Seemann, Torsten, Barbe, Valérie, Locht, Camille, Gutierrez, Maria-Cristina, Leclerc, Claude, Bentley, Stephen, Stinear, Timothy P., Brisse, Sylvain, Médigue, Claudine, Parkhill, Julian, Cruveiller, Stéphane, Brosch, Roland
Publicado em 2013