TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages

Mycobacterium tuberculosis (Mtb) strains are classified into different phylogenetic lineages (L), three of which (L2/L3/L4) emerged from a common progenitor after the loss of the MmpS6/MmpL6-encoding Mtb-specific deletion 1 region (TbD1). These TbD1-deleted “modern” lineages are responsible for glob...

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Publicado no:Nat Commun
Main Authors: Bottai, Daria, Frigui, Wafa, Sayes, Fadel, Di Luca, Mariagrazia, Spadoni, Dalila, Pawlik, Alexandre, Zoppo, Marina, Orgeur, Mickael, Khanna, Varun, Hardy, David, Mangenot, Sophie, Barbe, Valerie, Medigue, Claudine, Ma, Laurence, Bouchier, Christiane, Tavanti, Arianna, Larrouy-Maumus, Gerald, Brosch, Roland
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7000671/
https://ncbi.nlm.nih.gov/pubmed/32019932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14508-5
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