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The intersection of amyloid beta and tau at synapses in Alzheimer’s disease

The collapse of neural networks important for memory and cognition, including death of neurons and degeneration of synapses, causes the debilitating dementia associated with Alzheimer’s disease (AD). We suggest that synaptic changes are central to the disease process. Amyloid beta and tau form fibri...

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Bibliographic Details
Main Authors: Spires-Jones, Tara L, Hyman, Bradley T
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135182/
https://ncbi.nlm.nih.gov/pubmed/24853936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2014.05.004
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