Autism-related deficits via dysregulated eIF4E-dependent translational control

Hyperconnectivity of neuronal circuits due to increased synaptic protein synthesis is postulated to cause Autism Spectrum Disorders (ASD). The mammalian target of rapamycin (mTOR) is strongly implicated in ASD via upstream signaling. However, downstream regulatory mechanisms are ill-defined. We show...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gkogkas, Christos G., Khoutorsky, Arkady, Ran, Israeli, Rampakakis, Emmanouil, Nevarko, Tatiana, Weatherill, Daniel B., Vasuta, Cristina, Yee, Stephanie, Truitt, Morgan, Dallaire, Paul, Major, François, Lasko, Paul, Ruggero, Davide, Nader, Karim, Lacaille, Jean-Claude, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133997/
https://ncbi.nlm.nih.gov/pubmed/23172145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11628
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados