Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling

Protein synthesis is critical for circadian clock function, but little is known on how translational regulation controls the master pacemaker in mammals, the suprachiasmatic nucleus (SCN). Here we demonstrate that the pivotal translational repressor, the eukaryotic translational initiation factor 4E...

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Autores principales: Cao, Ruifeng, Robinson, Barry, Xu, Haiyan, Gkogkas, Christos, Khoutorsky, Arkady, Alain, Tommy, Yanagiya, Akiko, Nevarko, Tatiana, Liu, Andrew C., Amir, Shimon, Sonenberg, Nahum
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856944/
https://ncbi.nlm.nih.gov/pubmed/23972597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.06.026
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