Translational control of entrainment and synchrony of the suprachiasmatic circadian clock by mTOR/4E-BP1 signaling

Protein synthesis is critical for circadian clock function, but little is known on how translational regulation controls the master pacemaker in mammals, the suprachiasmatic nucleus (SCN). Here we demonstrate that the pivotal translational repressor, the eukaryotic translational initiation factor 4E...

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Detalhes bibliográficos
Main Authors: Cao, Ruifeng, Robinson, Barry, Xu, Haiyan, Gkogkas, Christos, Khoutorsky, Arkady, Alain, Tommy, Yanagiya, Akiko, Nevarko, Tatiana, Liu, Andrew C., Amir, Shimon, Sonenberg, Nahum
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856944/
https://ncbi.nlm.nih.gov/pubmed/23972597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.06.026
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