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Molecular basis for erythromycin-dependent ribosome-stalling during translation of the ErmBL leader peptide
In bacteria, ribosome-stalling during translation of ErmBL leader peptide occurs in the presence of the antibiotic erythromycin and leads to induction of expression of the downstream macrolide resistance methyltransferase ErmB. The lack of structures of drug-dependent stalled ribosome complexes (SRC...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4133097/ https://ncbi.nlm.nih.gov/pubmed/24662426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4501 |
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