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Molecular basis for erythromycin-dependent ribosome-stalling during translation of the ErmBL leader peptide

In bacteria, ribosome-stalling during translation of ErmBL leader peptide occurs in the presence of the antibiotic erythromycin and leads to induction of expression of the downstream macrolide resistance methyltransferase ErmB. The lack of structures of drug-dependent stalled ribosome complexes (SRC...

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Hlavní autoři: Arenz, Stefan, Ramu, Haripriya, Gupta, Pulkit, Berninghausen, Otto, Beckmann, Roland, Vázquez-Laslop, Nora, Mankin, Alexander S., Wilson, Daniel N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4133097/
https://ncbi.nlm.nih.gov/pubmed/24662426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms4501
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