PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium

At the early stages of carcinogenesis, transformation occurs in single cells within tissues. In an epithelial monolayer, such mutated cells are recognized by their normal neighbors and are often apically extruded. The apical extrusion requires cytoskeletal reorganization and changes in cell shape, b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Anton, Katarzyna A., Sinclair, John, Ohoka, Atsuko, Kajita, Mihoko, Ishikawa, Susumu, Benz, Peter M., Renne, Thomas, Balda, Maria, Jorgensen, Claus, Matter, Karl, Fujita, Yasuyuki
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists 2014
Aiheet:
Short Report
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132389/
https://ncbi.nlm.nih.gov/pubmed/24963131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.149674
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