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PKA-regulated VASP phosphorylation promotes extrusion of transformed cells from the epithelium

At the early stages of carcinogenesis, transformation occurs in single cells within tissues. In an epithelial monolayer, such mutated cells are recognized by their normal neighbors and are often apically extruded. The apical extrusion requires cytoskeletal reorganization and changes in cell shape, b...

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書誌詳細
主要な著者: Anton, Katarzyna A., Sinclair, John, Ohoka, Atsuko, Kajita, Mihoko, Ishikawa, Susumu, Benz, Peter M., Renne, Thomas, Balda, Maria, Jorgensen, Claus, Matter, Karl, Fujita, Yasuyuki
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4132389/
https://ncbi.nlm.nih.gov/pubmed/24963131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.149674
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