Rab5-regulated endocytosis plays a crucial role in apical extrusion of transformed cells

Newly emerging transformed cells are often eliminated from epithelial tissues. Recent studies have revealed that this cancer-preventive process involves the interaction with the surrounding normal epithelial cells; however, the molecular mechanisms underlying this phenomenon remain largely unknown....

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Saitoh, Sayaka, Maruyama, Takeshi, Yako, Yuta, Kajita, Mihoko, Fujioka, Yoichiro, Ohba, Yusuke, Kasai, Nobuhiro, Sugama, Natsu, Kon, Shunsuke, Ishikawa, Susumu, Hayashi, Takashi, Yamazaki, Tomohiro, Tada, Masazumi, Fujita, Yasuyuki
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2017
Soggetti:
PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5373379/
https://ncbi.nlm.nih.gov/pubmed/28270608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1602349114
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