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ADAM-like Decysin-1 (ADAMDEC1) is a positive regulator of Epithelial Defense Against Cancer (EDAC) that promotes apical extrusion of RasV12-transformed cells

Recent studies have revealed that newly emerging transformed cells are often eliminated from epithelia via cell competition with the surrounding normal epithelial cells. However, it remains unknown whether and how soluble factors are involved in this cancer preventive phenomenon. By performing stabl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yako, Yuta, Hayashi, Takashi, Takeuchi, Yasuto, Ishibashi, Kojiro, Kasai, Nobuhiro, Sato, Nanami, Kuromiya, Keisuke, Ishikawa, Susumu, Fujita, Yasuyuki
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6018119/
https://ncbi.nlm.nih.gov/pubmed/29941981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27469-z
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