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The paxillin-plectin-EPLIN complex promotes apical elimination of RasV12-transformed cells by modulating HDAC6-regulated tubulin acetylation

Recent studies have revealed that newly emerging RasV12-transformed cells are often apically extruded from the epithelial layer. During this cancer preventive process, cytoskeletal proteins plectin and Epithelial Protein Lost In Neoplasm (EPLIN) are accumulated in RasV12 cells that are surrounded by...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Kasai, Nobuhiro, Kadeer, Ailijiang, Kajita, Mihoko, Saitoh, Sayaka, Ishikawa, Susumu, Maruyama, Takeshi, Fujita, Yasuyuki
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794774/
https://ncbi.nlm.nih.gov/pubmed/29391412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20146-1
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