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Src-transformed cells hijack mitosis to extrude from the epithelium

At the initial stage of carcinogenesis single mutated cells appear within an epithelium. Mammalian in vitro experiments show that potentially cancerous cells undergo live apical extrusion from normal monolayers. However, the mechanism underlying this process in vivo remains poorly understood. Mosaic...

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Bibliografiska uppgifter
I publikationen:Nat Commun
Huvudupphovsmän: Anton, Katarzyna A., Kajita, Mihoko, Narumi, Rika, Fujita, Yasuyuki, Tada, Masazumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6224566/
https://ncbi.nlm.nih.gov/pubmed/30410020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-07163-4
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