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RESPONSE to Comment (Green) on "Evidence of abundant purifying selection in humans for recently-acquired regulatory functions" 1225057 Ward
Green and Ewing propose corrections to our methodology, which we incorporate and extend here. The improved methodology supports our initial conclusion of extensive lineage-specific constraint concentrated in ENCODE elements. We clarify that our estimate is dependent on the constrained and neutral re...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131756/ https://ncbi.nlm.nih.gov/pubmed/23661743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233366 |
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