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Patterns of variation in cis-regulatory regions: examining evidence of purifying selection

BACKGROUND: With only 2 % of the human genome consisting of protein coding genes, functionality across the rest of the genome has been the subject of much debate. This has gained further impetus in recent years due to a rapidly growing catalogue of genomic elements, based primarily on biochemical si...

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Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Naidoo, Thijessen, Sjödin, Per, Schlebusch, Carina, Jakobsson, Mattias
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5787233/
https://ncbi.nlm.nih.gov/pubmed/29373957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-017-4422-y
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