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HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

The resolution of genome-wide association studies (GWAS) is limited by the linkage disequilibrium (LD) structure of the population being studied. Selecting the most likely causal variants within an LD block is relatively straightforward within coding sequence, but is more difficult when all variants...

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Detalhes bibliográficos
Main Authors: Ward, Lucas D., Kellis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3245002/
https://ncbi.nlm.nih.gov/pubmed/22064851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr917
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