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RESPONSE to Comment (Green) on "Evidence of abundant purifying selection in humans for recently-acquired regulatory functions" 1225057 Ward
Green and Ewing propose corrections to our methodology, which we incorporate and extend here. The improved methodology supports our initial conclusion of extensive lineage-specific constraint concentrated in ENCODE elements. We clarify that our estimate is dependent on the constrained and neutral re...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4131756/ https://ncbi.nlm.nih.gov/pubmed/23661743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1233366 |
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