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Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis
Rheumatoid arthritis (RA) is a chronic autoinflammatory disease that affects 1-2% of the world population and is characterized by widespread joint inflammation. IL-1 is an important mediator of cartilage destruction in rheumatic diseases(1), but our understanding of the upstream mechanisms leading t...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4126806/ https://ncbi.nlm.nih.gov/pubmed/25043000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13322 |
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