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Repair of endogenous DNA base lesions modulate lifespan in mice

The accumulation of DNA damage is thought to contribute to the physiological decay associated with the aging process. Here, we report the results of a large-scale study examining longevity in various mouse models defective in the repair of DNA alkylation damage, or defective in the DNA damage respon...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Meira, Lisiane B., Calvo, Jennifer A., Shah, Dharini, Klapacz, Joanna, Moroski-Erkul, Catherine A., Bronson, Roderick T., Samson, Leona D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125484/
https://ncbi.nlm.nih.gov/pubmed/24994062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.05.012
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