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Repair of endogenous DNA base lesions modulate lifespan in mice
The accumulation of DNA damage is thought to contribute to the physiological decay associated with the aging process. Here, we report the results of a large-scale study examining longevity in various mouse models defective in the repair of DNA alkylation damage, or defective in the DNA damage respon...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4125484/ https://ncbi.nlm.nih.gov/pubmed/24994062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.05.012 |
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