Repair of endogenous DNA base lesions modulate lifespan in mice

The accumulation of DNA damage is thought to contribute to the physiological decay associated with the aging process. Here, we report the results of a large-scale study examining longevity in various mouse models defective in the repair of DNA alkylation damage, or defective in the DNA damage respon...

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Detaylı Bibliyografya
Asıl Yazarlar: Meira, Lisiane B., Calvo, Jennifer A., Shah, Dharini, Klapacz, Joanna, Moroski-Erkul, Catherine A., Bronson, Roderick T., Samson, Leona D.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125484/
https://ncbi.nlm.nih.gov/pubmed/24994062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2014.05.012
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