Imatinib Analogs as Potential Agents for PET Imaging of Bcr-Abl/c-KIT Expression at a Kinase Level

We synthesized two series of imatinib mesylate (STI-571) analogs to develop a Bcr-Abl and c-KIT receptor-specific labeling agent for positron emission tomography (PET) imaging to measure Bcr-Abl and c-KIT expression levels in a mouse model. The methods of molecular modeling, synthesis of STI-571 and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Peng, Zhenghong, Maxwell, David S., Sun, Duoli, Bhanu Prasad, Basvoju A., Pal, Ashutosh, Wang, Shimei, Balatoni, Julius, Ghosh, Pradip, Lim, Seok T., Volgin, Andrei, Shavrin, Aleksander, Alauddin, Mian M., Gelovani, Juri G., Bornmann, William G.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4124913/
https://ncbi.nlm.nih.gov/pubmed/24280068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2013.10.040
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